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Conclusion
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公司报告称，其实验性乳腺癌药物atirmociclib在一项中期临床试验中达到了主要目标。这是其肿瘤学管线向前迈出的一步。
2期FOURLIGHT-1研究在患有激素受体阳性、HER2阴性的晚期或转移性乳腺癌的个体中，考察了atirmociclib联合fulvestrant的效果。研究显示，无进展生存期明显优于常规疗法。
该试验包括264名已接受过CDK4/6抑制剂治疗的受试者。辉瑞报告称，该药物的安全性特征易于管理，约有6%的患者因不良事件而停止治疗。
总生存期（次要终点）的数据尚不完整，将在未来的更新中再次评估。该公司也在进行一项3期试验，以观察该疗法作为转移性癌症一线治疗的效果。
辉瑞还希望在即将召开的医学会议上展示另一项针对早期乳腺癌的2期研究的结果。
这些发现支持了辉瑞扩大其肿瘤学产品组合的更大计划。下一步的进展将来自更多的临床数据和正在进行的后期试验的进展。
